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Dual-pronged chemo-immunotherapy delivered using our bio-inspired nanotechnologies.
Bio-inspired nanotechnologies to aid risk stratification and therapy of deep vein thrombosis.
In situ vaccination nanotechnology. In collaboration with Dr. Steve Fiering, Dartmouth College.
Protein/polymer devices for slow-release immunotherapy. In collaboration with Dr. Pokorski, CWRU (contact PI).
Minimally invasive molecular imaging approaches using plant virus-based contrast agents to aid prostate cancer risk stratification.
Filamentous plant viruses as carriers for targeted drug delivery treating triple negative breast cancer.
Plant virus-based nanoparticle drug delivery targeting thrombosis.
Shape-engineering of a plant virus-based contrast agent for MRI imaging applications.
Plant virus-based nanoparticles conjugates for medical imaging and environmental sensing.
Case-Coulter Translational Research Partnership
Translational of plant VLPs for cancer immunotherapy. PIs: Steinmetz and Kim (UH Seidman).
CTSC Annual Pilot Award
Immuno-radiation combination therapy for cancer treatment. Team: Steinmetz, Kim, Oleinick, Patel.
Council to Advance Human Health
Virus-based in situ vaccination: understanding the underlying mechanism.
A plant virus-based breast cancer vaccine.
Team Science Award
T-cell vaccines targeting breast cancer. PI Shukla (Research Professor in the Steinmetz Lab), Co-PI Levine (MMB), and Co-I Steinmetz.
Plant virus-templated polymeric nanoparticles, in collaboration with PI Jon Pokorski (Co-PI Steinmetz).
Engineering novel filamentous plant viruses for cancer imaging and therapy
DNA and virus-programmed mesoscale assemblies, in collaboration with PI Roger French (Co-PI Steinmetz).
Nanomanufacturing went viral. In solution modification of Janus-type bionanoparticles, in collaboration with Co-PI Gobet Advincula.
Student exchange between TU Dresden in Germany and CWRU, in collaboration with Professor Rainer Jordan.
National Research Foundation
Grapevine virus targeting prostate cancer, in collaboration with the Vitis Lab at Stellenbosch University, South Africa (Professor Johan Burger and Dr. Hano Maree).
CMMI-1509232 RAPID Development of a bio-inspired probe for Ebola detection, in collaboration with Co-PI Ruth Keri.
Plant virus-based nanoparticles for imaging and therapy.
Ohio Cancer Research Associates
Plant virus drug delivery targeting breast cancer.
Steris Corporation for Infectious Disease (Pilot)
Purging persistant viral infection with nanoparticle 'seek and protect' therapy. Multi PIs: Steinmetz and Popkin (Dermatology).
Grant #IRG-91-022-18 (Pilot Award)
HER2 immunotherapy using a plant virus-based vaccination platform.
NIH P30 CA043703 (Pilot Award)
Multi-stage delivery of nanomaterials and their cargos targeting breast cancer. PI Steinmetz, Co-PI Keri.
Interdisciplinary Alliance Investment Grant (IAIG): Innovation Pilot Grant
Core-shell nanoparticles for image-guided therapy. Multi-PI collaboration: Steinmetz and Samia (Chemistry)